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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dde1c4351df45e6c3d29e063ee7ccb8cd05f3383b165e0c9a4cd288a867f734' 
  AND token = 'TQQ0H16jcOQeESi4HHiB/GqeEU0fV2WNz4+DHFTDP5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}