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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da564d1a72045e3d851aeb7b6c77cea4c756a4065e2691c9c3db46bda6f4f83f' 
  AND token = 'wACmsV9tmnUXKP6+b+0RSbRN/vPJsRBbHUZk3Qf+Rhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}