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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7212f6b76536896be7f802aa972539e1b8bc1d5275b9fb7fc56c380a69de28d3' 
  AND token = 'S7kWLaNEchOzQ1wTLFg+TdKp8pSZwFR7wN2jMlvCAr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}