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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fb25c887e93f8cbfb128dea16722896e29c02480aeadabd035e3f020964a0cd' 
  AND token = 'wlICcXp7WBsLMauvAoNXj6lgQtdcSl1Cxteaws3AFOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}