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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c6cb1e1787baac1c5f9ee8095dff056a6b8431c83559e85004c269ee08c8879' 
  AND token = 'xdZir2xOX/krmkXzngNu5bfirWBNL06xxi/Zc2X0RPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}