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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ad570d300ee38f70b98ff2d24e33917061ae1b197cb4ee5aee20c9d32ef5066' 
  AND token = 'pwTIcBJTVEPt0a+HYNK5DfRRIRBdh4+OboThNYX6zUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}