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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41cc0f1cb47f74f60f6875b4eb252e7c90b228c3740428b2c40201f08e8b7277' 
  AND token = 'PSdq0pAkewSPIV9unk18i2VvYBGwM/dZu/YrYlu397Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}