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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd34489ee96cd32a9a234db569cf362da26626a74967c029fd9e399c4aa1b0543' 
  AND token = 'ge+8Us4FNWuIBkoc65VhJgaPZLaO8pv1ElFxpmi7DyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}