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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab4b2aee3e0ff13ce9a70895d3f130fd3470c2438084d6bf503c62b3b2f0d2d9' 
  AND token = '+Op7dMNbZcG+Jvdbg8vs5fS5qVEZKPPW167TM0Dt2cE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}