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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50770b8e71ee28f14e78e9052c5d65146c13b901b31712e39a5be7b64ef7c4cd' 
  AND token = 't0/0zIjUfM7wbRUDkEFeGM5e9vTy1NoGh7sxYVh7i0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}