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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3f3e0e2b49a472af4f4aeefea39d277108e60065080d87e489cae1b154b0283' 
  AND token = '8cXISYKuQpxnH/6InkxSDnvxwYyo4p79OONzc5Wei6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}