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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c755b73ed793f9b4a4a1675fb8ba00253f107f30851815aa55d1bd04ab0453a9' 
  AND token = 'Q9b4tvt1xlLpoTSUKh7bMn2Ydco9t+7tcJc0dp4GObQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}