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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64448e3c66ee1388e1c6a79f89b8cd4445876a6af1894a415e9c7aec6716a989' 
  AND token = 'sk8E/D7Gu/pXV4PV/YYgBXE/gQ9W5KdSvj96LZxK8RM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}