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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f61b431efabdcd5bb0d0994898a3f1f58a359d4005fedb5eff4da387c442144' 
  AND token = '4i8A/wCf+r4QInKTV+JYKq/pnysYl/cqXD9y0jsl3ZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}