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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '980c6ef7af27a04f4ede5ce5111168eda481773e1d4a7debf037d677db0c9535' 
  AND token = 'sXcbRU5O6eYBz8C/DsHPLisOH33mxg/Q/zlPQmS1Q28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}