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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aac0109449372b081a7001bcb33447cf52d2b44a238efc002b76ef54cf5afbc6' 
  AND token = 'lj4ucK/kz0GGnpnz4LKFruAmmpFweIkGNC37/O/MybA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}