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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41cf4ce18efae58be12e1ff7bc19f94218de61cb74c0cd67a3df40f9a920e215' 
  AND token = '2BetjtT5uJzAWMRVzYSy9Tw5x/uO5NSRv7VcuMBVkZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}