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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '288a96d3b2b0a052902c1ff9655a9ef2e517d99cc243bd0b9a27be6f265355c0' 
  AND token = 'KD9nqncwd/0Wz1MTpDf4H7c66baLCwDTPVEIqWthTy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}