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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b59cb34f8c7c64a9585ae5b34438649c53a39c691bd5be77f4465665c3b5d6a' 
  AND token = 'dGUhAromaETDkOLj5gHcZ+WLMff1/IBSG4+kPjXmw/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}