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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1376ad347cb14d97299af3268b0b75d39794961c9def9214e7712ae2b7b9af4' 
  AND token = 'skxYy6L2kCEjk6euOU+BN5bIKLnU0EHDOy8gN4dOptw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}