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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5c5455af639ece2f538d0f48cfc2f7c0db832ea0a480628eaee44e6c2c65434' 
  AND token = 'yXiIuyNq0KhZNvEt3R6Nr8YNnJEQ/ykcNbQdP72rOKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}