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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d37c1301a9c79528ae44f8bb8e8416786f5f9aa0401da59c7b36db43523534a' 
  AND token = 'cUx5vVGz2gmNiUWZtouLyQhZ6p2R/c85EE4xaPfJeUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}