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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aed0fc549c33f4e338d83e35771220f52ac94c5efd2de9a65171c44714915a24' 
  AND token = 'TYwVwJYmk3mlilaMhwJ81QwrzXFfkaln8gjH3XR8iRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}