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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7d045324ced2f8c7dd27830f4acdd20a0d1bf2ce3f9e9009d0da3363c4a5276' 
  AND token = '5QJqfEKygNPTxKFExAm4BW7CR15UI2JW4xkoqenz1NA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}