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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35c101c3990e79f63e539d62389bdc5bc3c4768655a83e0dd94b1616e6e7a126' 
  AND token = '8qtxgOGs4I9b/BZSKJpZEjiOScqX2ZE01hnxombZxj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}