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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e3b25f5665444f02c3a7165b055dcab079afec3e0baf9e42f51808c3b62a141' 
  AND token = '5Mw5SPYfFHVO3g7PclG9Xq1dVOQbmNCwDea1iXdOCAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}