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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea1743c4dcd34adf53be9ec8f25e7775a85c10a43b833ef1594c6e50fe51d21f' 
  AND token = 'vJBRxODk6lch14rX/Xgp1x5k8rzijKy+mbcEgCMzpvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}