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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b7ea462533ae3748e75d4b5096832df91fbde5469c7934644cfd0745108c054' 
  AND token = 'rR9ycxNmaDv1UOXi9fWIKSWpEw6RreZiLaOJPNz58rU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}