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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eae3a13e0618992fac25ea48a822d17e964c0cf1af25f3f74d6a56c29908024' 
  AND token = 'S2wc/oM6mxuorkG+E/+mf7VTZbwNZGLaXXz9ENPyI44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}