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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7465c4ec49e8eb26d8d52ea5199cb7e008de9703991552d9039a4ae49c32b121' 
  AND token = 'PWFr8zXKK7tDZfqTOuw/z+70HUctpLXx/8bl4Juel+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}