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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8dabd26512b204bb8a4c577986b975a5ca539697058d8ab7809b15e2545aa8d' 
  AND token = 'GXkRbHdmytvU1VukBCRTR7du5ao/PAxEg5XkGwc6udM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}