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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b4f871685115f5a0d2df14b3e4290e15a13e9283b9420845a89f2a241de04de' 
  AND token = 'pjooqivLvCH1kTUdqanWRGsGCWtnqIoePK00wb0ueOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}