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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3ecd3123253df79600561866c0d015913591754f3e3b35a8d062c02304d5161' 
  AND token = '6AJ+OfA9I/czyYaDg5l45ExGiCW8cf3Mr5eaR7yk0Ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}