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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45c14a3b33aa7a8092db058246bd44312ed256a241fa761d5e64281c3f731876' 
  AND token = 'JArfO5MMGqWHcthnWO3GPiEt5dpLjbaJDm57sT3x9fA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}