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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2c3abb71c8440fee9f3c02d1371297cb8eda227aab7ba04f46606f8afac3321' 
  AND token = 'ZWCG7L09uFU1h/wtvYKw1lQ8pTovUnaosbiRSZ8hvgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}