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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff4cc16b137ddf62e7f93900f229d7e8d012edfbd3faf111a4ac6214bb947521' 
  AND token = 'pSp3Mb0BKSmTNGpmQ+pDPwnU4yMiinFFWe7qCD14ams=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}