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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '789cab5250b2c5da975d41539f98aade94f68e2a8631926fb549bd8be10ebdd8' 
  AND token = 'JzXHeGviTbMWkNOGNOYxi7PnXXOrW+VgIY9EuLc3ORs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}