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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45c3ba6eaf5cd4ce6f94d316362a30e395953ea000bd177c44bac36e51e4c7ff' 
  AND token = 'kDoRFsCIK1rQEU4f46kvFDCHknOnqvra6xgIAn752wE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}