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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cb171138bbb2f3bbd084d87278974a6be5251ade88f65e6b20a071148a2eb0b' 
  AND token = 'PtjNV/b+RqvqohriErKHcC/XSdG5q8e4hst33/oHQZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}