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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5a054104e8f209dd57b5fedaf5c9dd3d66b0ae6143224490cad193b7326449a' 
  AND token = '3DuZwXKbNcL51J3f8PZVh40SzdsY8AsipP7GQM7s66E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}