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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c518adde89d49a01fc656878a1f6c18f21d832cbaac4b9e33fd03d7eba063b1' 
  AND token = 'pRoHkhksslR2JaERnvI6bNNzOUvQOfz3ESKFvxW8Gvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}