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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e550c917cff0722b82b63f48b6ed1817a5bf499d727f411ad0e4e4789deee77' 
  AND token = 'Pvj+xcDQCjidF78ZYMPW1B0+7yZSv9RQlQGoCEeEMPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}