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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff4ce29f46c680e8226cd16960345742f4ea838da94d17f5228e28d0eb718f21' 
  AND token = 'xLI8a7CXkUYx99RL0JqNr+IJcrBE2Lc8Pr+q54NFfjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}