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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e6410ebdb5d5a046c55d30d5cb422463a82a5cd67c5e151f4d1fc6b71fc6abd' 
  AND token = '2noszExIlO6DE6TGNkWvG9OY9Of9XvanOPaWFtS9cPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}