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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c46d5b48b27099a09e800a11ee931aaeb39d2556b0ddbcd71168bf386277b490' 
  AND token = '0c1d6W6UBlsMFdcrtZPd6dXE1nSDJJrfwT7JTT7jb6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}