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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e74fdc4e629b926e8922d6d1dfb30db341fed9b9b19aea14d1eefa1f8ba18db1' 
  AND token = 'AGvnyf/xwgHSw9qJ6b39btn2DSsTSRyxuu4+yQbb+LE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}