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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ed361f36c71714ad9285261b692e20475b36c89a7bb3a3c289cc05b377f39a7' 
  AND token = 'yxX/VB576wilBLL82XdUPu4vDeOMZm/WLGH9nc4J2mk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}