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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bdf7207e23296c9a2b20b284b9f06c80adf936539a18347b7db98645de30357' 
  AND token = 'LtNfPhZnUqe4X2mj2iNfn2vvB8EwLcyDKaeSZEvREj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}