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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f658e2f890ee2f7726d47787a52a2ca55b55771ff91fa17c90e4b89f21ac72c' 
  AND token = 'HNJv4ovZHulH+dIP5hRu2kVFzhYxTP7kS6I8JQ8Ks5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}