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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6480d77b494231687819a55f5c49093b72ab53e3ff2d61c4515e97598d87fd62' 
  AND token = 'YG77GtxfpvcyzWOL6VzZA9AThFWvCv0avQEhqf58hdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}